The process typically begins with blending active ingredients and excipients. Uniform mixing is essential because even slight variations can lead to inconsistent dosing. Advanced blending equipment ensures equal distribution of ingredients before granulation.
Granulation improves powder flow and compressibility. Wet granulation uses liquid binders to form particles, while dry granulation eliminates moisture exposure for sensitive drugs. Selecting the appropriate method depends on chemical stability and formulation goals.
Tablet compression represents one of the most critical stages. Pressure applied during compression must create tablets strong enough for packaging yet capable of dissolving efficiently in the body. Sensors monitor weight, hardness, and thickness continuously.
Coating technologies enhance both functionality and appearance. Enteric coatings protect drugs from stomach acid, ensuring release occurs in the intestines. Film coatings also mask unpleasant taste and improve swallowing comfort.
Quality testing plays a vital role throughout manufacturing. Dissolution testing evaluates how quickly medicine releases active ingredients, while…